Holyfield, on the other hand, had gone 2-2 in his last four fights and had suffered the first stoppage loss of his career in a third fight against Riddick Bowe just one year earlier. Oddsmakers listed Tyson as the 1/25 favorite at the open before settling around 1/10. Some in the boxing media at the time of the event were even afraid for Holyfield’s life.  Andy Ruiz, 29, from Imperial, California, shocked the boxing world at Madison Square Garden in New York. Coming into his second world title challenge on just about a month’s notice as a late replacement opponent for Jarrell Miller, Ruiz rose from the first knockdown of his career in the third to drop Joshua four times over the next five rounds before referee Michael Griffin stopped the fight. By the seventh round, Joshua, the 1/24 favorite, stood weary-eyed in the corner, concussed with disbelief that Ruiz was standing in the center of the ring hands raised high in jubilation after completing one of the biggest upsets in boxing history.