Born in Los Mochis, Sinaloa, Mexico, Beltrán beat the veteran Moises Pérez to win the WBC Continental Americas Super Featherweight Championship in March 2008. In July 2012, Beltran, trained by Freddie Roach and a sparring partner of Manny Pacquiao, won the WBC NABF Lightweight title in an upset with a majority ten-round decision over the WBC number one lightweight contender Henry Lundy. Before the bout, Lundy had to weigh in four times to make the 135 pound limit. Beltran, in top condition, came forward more aggressively and landed more punches overall by the CompuBox statistics. With the win, Beltran won the opportunity to fight the winner of Antonio DeMarco versus John Molina for the WBC Lightweight title for the title later in 2012. Beltran defeated Ji-Hoon Kim by unanimous decision to retain the NABF lightweight title in December 2012.

WBO Lightweight titleholder Ricky Burns' promoter Eddie Hearn announced a title defence against Beltran at the Scottish Exhibition and Conference Centre on September 7, 2013. Beltran knocked down Burns in the 8th round. The bout ended in a controversial split-decision draw. Many observers believed Beltran had clearly won, Burns fought on from as early as the second round with a broken Jaw and the draw was awarded. 

Hank Lundy....................fight 32

Kim Ji-hoon...................fight 33

Alejandro Rodriguez...fight 34

Ricky Burn......................fight 35

Arash Usmanee............fight 36

Terence Crawford........fight 37

Takahiro Ao....................fight 38

Ivan Najera.....................fight 39

Mason Menard.............fight 40

Jonathan Maicelo........fight 41

Bryan Vázquez..............fight 42

Paulus Moses................fight 43

José Pedraza................fight 44

Hiroki Okada.................fight 45

Richard Commey.........fight 46