Juan Manuel Márquez vs. Manny Pacquiao I, billed as Hearts and Fists on Fire, was a professional  boxing match contested on May 8, 2004, for the WBA (Unified), IBF, and The Ring featherweight title.

Juan Manuel Márquez vs. Manny Pacquiao II, billed as Unfinished Business, was a professional        boxing match contested on March 15, 2008, for the WBC Super featherweight championship.

Manny Pacquiao vs. Juan Manuel Márquez III, was a professional boxing match contested on              November 12, 2011, for the WBO welterweight championship.

Manny Pacquiao vs. Juan Manuel Márquez IV, billed as "Fight of the Decade", was a professional boxing match contested on December 8, 2012 at the MGM Grand in Las Vegas, Nevada. This was the fourth and   final meeting between Pacquiao and Márquez